Immunomodulatory and Natural Immunomodulators

The immune system is a remarkably developed defense system inside vertebrates which guards against attacking factors. It is capable of producing diverse molecules and cells able to distinguish and reduce unlimited changes from external and unwanted agents. Modulation of the immune system refers to some alteration in the immune response which includes stimulation, amplification, expression or inactivation of some stage of the immune response. Therefore, an immunomodulator is a material used to have an effect on the immune system. There are commonly two kinds of immunomodulatory depending on their influence: immunostimulators and immunosuppresses [1]. Materials, which show a modifying immune system response to a threat, are immunomodulators. They modulate and arm the immune system by keeping them in a highly prepared state against any threat [2]. In different parts of the world, plant extracts have been widely investigated for their possible use for immunomodulation.